On World Food Day, October 16th, New York City’s food trucks are donating 5 percent of their sales to help international humanitarian organization Concern Worldwide fight extreme hunger in the world’s poorest countries.Participating trucks include: Gorilla Cheese NYC – @gcnyc1, Chinese Mirch – @ChineseMirch, Milk Truck – @milktrucknyc, Toum – @ToumNYC, Valduccis – @valduccis, Phil’s Steaks – @PhilSteaks, Snap – @SnapTruck, Mexico Blvd – @MexicoBlvd, Red Hook Lobster – @Redhooklobster, Nuchas – @NuchasNYC, Souvlaki GR – @SouvlakiTruck, and Shorty’s on Wheels – @ShortysNYC.“We are deeply grateful to the New York City Food Truck Association and all of the trucks who are coming out on World Food Day to help us make hunger history,” said Sarah de Tournemire, Development Director at Concern Worldwide US. “Each and every meal purchased tomorrow at the participating trucks will be so much more than just a meal—it will help reach more malnourished children who are in need of treatment and help more communities break the cycle of hunger.”To find specific location information, follow the participating trucks on Twitter. Updates will also be available throughout the day on Twitter @Concern and @nycfoodtruck.Five percent of participating food trucks’ sales on World Food Day, October 16th, will specifically support the Concern for Hunger campaign, a movement against extreme hunger that Concern launched last month with award-winning actress Toni Collette. All donations to Concern for Hunger support Concern’s programs that treat and prevent malnutrition in the world’s poorest countries.To learn more about Concern for Hunger and how you can make a difference, watch this message from Toni Collette and visit ConcernUSA.org.
Rank 1.37 million 2 Program THE WALKING DEAD (AMC) 2.13 million 5 THE BIG BANG THEORY (CTV) 1 A18-49 (CTV has 6/10) 276,000 10 Facebook 2.82 million 3 LEAVE A REPLY Cancel replyLog in to leave a comment 8 478,000 3 614,000 1 5 1.91 million THE BIG BANG THEORY (CTV) Data from Numeris also confirms that:YOUNG SHELDON:YOUNG SHELDON marks the biggest debut for a new comedy series in at least 10 years.YOUNG SHELDON is the first new comedy series in at least 15 years to debut in the Top 5 in the fall.For the first time since 2012, two comedy series have landed in the Top 2 spots (THE BIG BANG THEORY and YOUNG SHELDON), each averaging over 1 million viewers (A25-54).THE GOOD DOCTOR:THE GOOD DOCTOR, starring Golden Globe nominee Freddie Highmore as Dr. Shaun Murphy, is the #1 new drama in Canada with P2+, A18-34, A18-49, and A25-54After a strong series debut (the second biggest debut of Fall 2017 with P2+), THE GOOD DOCTOR on CTV marks the first time in at least five years that a top new program has seen consistent weekly growth over its debut episodes, with four weeks of consecutive audience growth at the beginning of the season (P2+).THE GOOD DOCTOR is also up double digits vs. debut episodes with all key demos in its last three episodes this season, which averaged more than 1 million viewers (A25-54) each.On Nov. 20, THE GOOD DOCTOR peaked at 3 million total viewers and 1.2 million A25-54 viewers.Additionally, CTV’s latest original event series THE INDIAN DETECTIVE starring Russell Peters, is the #1 new Canadian series this fall and marks the biggest debut episode for a Canadian scripted series since 2011.Canada’s Top Programs – Fall 2017 Season:Total Viewers (CTV has 7/10) Advertisement 3.14 million 10 YOUNG SHELDON (CTV) 1 250,000 GREY’S ANATOMY (CTV) 1.04 million HOCKEY NIGHT IN CANADA (CBC) 1.541 million 3 BLUE BLOODS (CTV) 1.45 million 8 6 Program 395,000 2 THE WALKING DEAD (AMC) THE BIG BANG THEORY (CTV) 9 WILL & GRACE (Global) THE GOOD DOCTOR (CTV) Rank 1.16 million 4 GREY’S ANATOMY (CTV) GREY’S ANATOMY (CTV) 10 Advertisement 391,000 9 5 5 P2+ Advertisement 1.86 million 961,000 1.89 million 7 Program 1.24 million THIS IS US (CTV) DESIGNATED SURVIVOR (CTV) 1.537 million 9 255,000 Rank TORONTO – With the Fall 2017 television season coming to a close, Numeris data confirms another incredible performance for CTV, as the network’s Fall strategy delivered a primetime lineup of heart and soul, family-friendly, co-viewing programming to its viewers. CTV has landed – for the first time on record in the fall – the Top 3 most-watched programs for total viewers (P2+) and all key demos (A18-34, A18-49, and A25-54), including THE BIG BANG THEORY, YOUNG SHELDON, and THE GOOD DOCTOR.The achievement comes with CTV also delivering Canada’s Top 3 new programs with total viewers: YOUNG SHELDON, THE GOOD DOCTOR, and THE INDIAN DETECTIVE. Overall, CTV delivered more Top 10 programs this fall than any other network, with 40% more viewers than its closest competitor in primetime among A25-54.CTV is home to the most-watched series and comedy (THE BIG BANG THEORY), the most-watched new series (YOUNG SHELDON), the most-watched drama (THE GOOD DOCTOR/GREY’S ANATOMY), the most-watched Canadian series (THE INDIAN DETECTIVE), and with all key demos THIS IS US is the most-watched sophomore series this fall. Program .SOCIAL MEDIA LINKS:Twitter:@CTV_TelevisionFacebook:Facebook.com/CTVInstagram:CTV_TelevisionAbout CTVCTV is Canada’s #1 private broadcaster. Featuring a wide range of quality news, sports, information, and entertainment programming, CTV has been Canada’s most-watched television network for the past 16 years in a row. CTV is a division of Bell Media, Canada’s premier multimedia company with leading assets in television, radio, digital, and Out-of-Home. Bell Media is owned by BCE Inc. (TSX, NYSE: BCE), Canada’s largest communications company. More information about CTV can be found on the network’s website at CTV.ca.Source: Numeris, Fall 2017 (Sep 25 – Dec 17, 2017). Includes playback up to December 18, 2017. Primetime Monday-Sunday 7-11 p.m.CTV electronic audience databases and Top 20 records incorporate data beginning in 1994 and 2004, respectively. Audiences prior to August 31, 2009 based on BBM Nielsen Media Research Mark II meters. 993,000 2 THE GOOD DOCTOR (CTV) 10 YOUNG SHELDON (CTV) A25-54 (CTV has 5/10) SURVIVOR (Global) 7 928,000 WILL & GRACE (Global) SURVIVOR (Global) THE BIG BANG THEORY (CTV) THE GOOD DOCTOR (CTV) GREY’S ANATOMY (CTV) 796,000 574,000 9 A Fall of Firsts and Frontrunners: CTV Delivers the Top 3 Most-Watched Programs This Fall ### CTVs Humanity, Humour, and Heart Fall Strategy Pays Off with Viewers. Source: Numeris, Fall 2017 (Sep 25 Dec 17, 2017). Includes playback up to December 18, 2017. Primetime Monday-Sunday 7-11 p.m. CTV electronic audience databases and Top 20 records incorporate data beginning in 1994 and 2004, respectively. Audiences prior to August 31, 2009 based on BBM Nielsen Media Research Mark II meters. (CNW Group/CTV) A18-49 YOUNG SHELDON (CTV) A25-54 567,000 NCIS (Global) THE WALKING DEAD (AMC) HOCKEY NIGHT IN CANADA (CBC) STAR TREK: DISCOVERY (Space) THE FLASH (CTV) 579,000 THE FLASH (CTV) 6 607,000 Rank A18-34 8 247,000 354,000 7 2 YOUNG SHELDON (CTV) A18-34 (CTV has 6/10) 3 4 808,000 THIS IS US (CTV) 856,000 560,000 4 HOCKEY NIGHT IN CANADA (CBC) 6 6 523,000 STAR TREK: DISCOVERY (Space) 7 621,000 636,000 THE GOOD DOCTOR (CTV) BULL (Global) SURVIVOR (Global) 291,000 2.76 million 597,000 SURVIVOR (Global) 641,000 8 1 THIS IS US (CTV) 4 Login/Register With: THE INDIAN DETECTIVE (CTV) Twitter
NEW YORK, N.Y. – Pictures of mice lounging around an anti-rodent device designed to make them flee were cited by a judge who let a class-action lawsuit proceed Wednesday against a company that sells and markets them.“It is often said that a picture is worth a thousand words,” U.S. District Judge William H. Pauley III wrote above three pictures depicting mice near and, in one case, resting on top of the device. “And, in this case, three photographs from a study conducted by plaintiffs’ expert are worth even more.”Then he noted that lawyers had submitted over 42,000 words to try to convince him how to rule.“As the photographs show, mice can apparently relax comfortably under a Repeller and even appear to be so drawn in by its siren song that one would scale a wall just to snooze on it,” Pauley said, citing a photograph of a mouse, it’s tail dangling beneath it, climbing up a wall to the device.The 2015 lawsuit was filed by women in Palm Desert, California, and Woodville, Texas. They sought unspecified damages and wanted the lawsuit to represent others who had purchased over 2.4 million devices.They said they bought Bell + Howell Ultrasonic Pest Repellers based on advertising that claimed the devices were “fast and effective” to repel “mice, rats, roaches, spiders, and ants” and “Drive Pests Out.”They sued in Manhattan federal court after concluding the devices, which plug into an electrical outlet, were ineffective, naming as defendants the New York-based BHH, LLC., which does business as Bell + Howell and Van Hauser LLC.In ruling, Pauley noted that some packaging for the devices includes a disclaimer that says ultrasonic signals will lose intensity as it travels and that it can be absorbed by soft objects such as carpeting and is reflected by hard surfaces such as furniture.“But whether this disclaimer puts consumers on notice is a jury question,” Pauley said. He added that a jury could decide if the devices are completely ineffective and falsely marketed.Attorney Adam H. McCabe, representing the companies, said Pauley’s ruling on the request to dismiss the lawsuit without a trial was disappointing.“Our client stands by its product and the product’s effectiveness,” he said. “Numerous scientists and laboratory testing of ultrasonic pest repellers confirm their effectiveness. It’s unfortunate that the photo, taken by plaintiffs’ paid experts in a staged and unverifiable setting, was included in the Order.”Pauley said the company might have been on notice that ultrasonic repellers were generally ineffective based on warning letters the Federal Trade Commission’s Division of Enforcement sent to 60 manufacturers and retailers of ultrasonic pest-control devices, saying claims about the products had to be supported by scientific evidence.He noted that the plaintiffs also had cited “a cavalcade of studies” published before 2011 that they said proved the devices were generally ineffective.
New Delhi: An associate of Kashmiri separatist Aasiya Andrabi, arrested in a case of allegedly waging war against the country with support from Pakistan, opposed in a Delhi court Thursday the NIA plea for recording her voice sample for their investigation.A lawyer appearing for the accused — Nahida Nasreen — told Special Judge Rakesh Syal that the National Investigation Agency’s demand for her voice sample was not permissible under the law. Also Read – Uddhav bats for ‘Sena CM’According to a court source, NIA told the court that it had some audio recordings related to their ongoing investigation with which the agency required to match Nasreen’s voice. The submissions were made before the court during an in-camera proceedings. The court in December last year directed NIA to hand over the copy of the charge sheet and other documents filed along with it to Andrabi, chief of the banned outfit Dukhtaran-e-Milat, and her two associates Nasreen and Sofi Fehmeeda. Andrabi, Fehmeeda and Nasreen are currently in judicial custody. The charge sheet and the documents, which also include electronic copies of the accused’s speeches, videos and social media links, were handed over to the accused. The court posted the matter for further hearing on May 6.
One of India’s most-read authors, Ruskin Bond has said that he tries to strike a positive note when writing for children and feels a certain responsibility as an author. The Landour-based writer, when asked what he felt about his vast readership, said that since he writes so much for young readers, he tries to strike a positive chord. “For adults, it doesn’t matter, you can strike a negative note, because by the time they’ve grown up, they lose their innocence,” the 84-year-old Padma Bhushan recipient said at an event. Also Read – An income drop can harm brainSharing nuggets from his own childhood, the author of ‘The Blue Umbrella’ (also cinematically adapted by the same name), said that he shares a deep connection with the hills. “I belong to the hills. Surroundings change, the place changes a bit, but my relationship remains more or less the same, my feelings for the hills and for the people of the hills,” the author said. “It goes back 50 years or more. I don’t like to see too much change, in the sense that I don’t like too much building, but it’s inevitable,” he further added. Also Read – Shallu Jindal honoured with Mahatma AwardNow, in an upcoming compilation of 14 holiday stories for children – ‘The Puffin Book Of Holiday Stories’ – Bond’s young readers will be treated to one of his another literary gems. His latest children’s story is published in the just-launched fun anthology of adventure, humour, ghosts, mysteries, friends, mangoes, family dramas and little boys and girls. If the list of authors is nothing short of illustrious – Rabindranath Tagore, Sudha Murty, Paro Anand, Khyrunnisa A, Subhadra Sen Gupta, Nandini Nayar, Prashant Pinge, Himanjali Sankar, Nayanika Mahtani, Shabnam Minwalla, Manjula Padmanbhan – the children’s book comes with an introduction by Bond. “In India, not enough importance is given to writing for children. And what could be more important than the enrichment of young minds with great literature? “This is when we discover ourselves, our own potential, and, more often than not, we’ll do it through what we read and write,” reads his short introduction to the paperback. Advising his young friends to take a bag full of books wherever they go, he said: “Holidays can become tedious without something to read.”
Welcoming Sri Lanka as a new member of the OGP, Minister of Justice Wijeyadasa Rajapakshe, who headed the Sri Lankan delegation to the OGP Global Summit currently being held in Mexico City, was accorded the honour of being the first plenary speaker at the inauguration presided over by Mexican President Enrique Peña Nieto. Sri Lanka endorsed the Open Government Declaration committing “to foster a global culture of open government that empowers and delivers for citizens, and advances the ideals of open and participatory 21st century government,” thereby becoming the newest participating country of the Open Government Partnership (OGP).Sri Lanka is the only South Asian participating country in the OGP and joins other countries in the Asian region such as Indonesia, Mongolia, Philippines and Republic of Korea. The Open Government Partnership is a multilateral initiative by the United States launched in 2011 to provide an international platform for domestic reformers committed to making their governments more open, accountable, and responsive to citizens. From its initial 8 countries – Brazil, Indonesia, Mexico, Norway, Philippines, South Africa, United Kingdom, United States – the OGP has now grown to 69 participating countries, encompassing countries of both the developed and developing world. OGP aims to secure concrete commitments from governments to promote transparency, empower citizens, fight corruption and harness new technologies to strengthen governance. In the spirit of multi-stakeholder collaboration, OGP is overseen by a Steering Committee, which includes representatives of governments and civil society organizations. Addressing the plenary Minister Rajapakshe said that “the Government of Sri Lanka has decided to join the OGP, extending recently initiated good governance practices towards an open government and that “the Open Government Declaration that Sri Lanka has just endorsed is very much in line with our government’s vision for Sri Lanka.”He said, “as Sri Lanka joins the OGP, we recognize that the threshold required to be a truly open government has been raised. This makes us even more determined to walk this path together with participating states of the OGP and civil society members, learning from your experiences, and obtaining expertise whenever necessary to build our own capacities, to reach the required benchmarks. And as our government has already demonstrated, we keep our promises.” The first step towards full OGP participation is meeting the OGP eligibility criteria. In order to be eligible to participate in OGP, governments must demonstrate a minimum level of commitment to open government principles in four key areas of Fiscal Transparency, Access to Information, Income and Asset Disclosures, and Citizen Engagement. Sri Lanka became eligible to join earlier this year, having met the required criteria and scoring 14 of a total of 16 points.The delegation to the OGP summit also included Deputy Minister of Foreign Affairs Dr. Harsha de Silva, Sri Lanka’s Ambassador to the US Prasad Kariyawasam and officials of the Embassy of Sri Lanka in Washington D.C. and the Ministry of Justice.
Secretary-General Kofi Annan today appointed a senior banking executive from Italy as the new Director-General of the United Nations Office at Vienna (UNOV) and head of the UN Office for Drug Control and Crime Prevention.Antonio Mario Costa, who replaces Pino Arlacchi, also a national of Italy, is currently the Secretary-General of the European Bank for Reconstruction and Development in London.From 1987 to 1992, Mr. Costa served in various capacities at the Commission of the European Union, rising to the post of Director-General for Economics and Finance. Earlier in his career, he served as an economist in the UN Department of International Economics and Social Affairs, where he became Head of Unit.Mr. Costa, who has a PhD in economics from the University of California at Berkley, was also a visiting professor in various universities in Europe and the United States.
Check out FiveThirtyEight’s March Madness predictions. The shading shows you the general range of strengths for each seed.Although not a huge effect, the gap between the No. 5 and 6 seeds and their competition has been narrowing over time. The average difference between No. 5 and 12 seeds from 2000 to 2002 was about 7.6 points, but it has been about 5.8 from 2012 to 2014.More importantly, the 5 vs. 12 matchup looks a lot more like the 6 vs. 11 one than it does the 4 vs. 13. The No. 5 seeds have been considerably weaker than No. 4 seeds, and No. 12 seeds have been considerably stronger than No. 13 seeds. The average No. 5 seed had a 6.6 point expected advantage going into a game against its No. 12 seed opponent. That’s only 2.2 points higher than the average advantage that No. 6 seeds held against No. 11 seeds (4.4 points), but it’s 5.1 points lower than the average advantage that No. 4 seeds held against No. 13 seeds (11.7 points).It seems like the 5 vs. 12 seed matchup is the threshold where the games should start being much more competitive. Combine that with the psychological effect of thinking five is a number that has more in common with four than six (blame our five fingers), and you have a recipe for “shocking” upsets.That is, there are a number of upsets, but we shouldn’t really be shocked. Even just looking at recent history, No. 5 seeds have only been a greater than 10 point SRS favorite in eight round-of-64 games since 2005, and they won 7 of them.3The loser was Illinois against Western Kentucky in 2009. The No. 5 seed has been an SRS underdog three times (and lost twice). Still, the No. 5 seed has performed below what one would expect based on the difference between them and their opponents. But so have most seeds. Here’s a chart comparing the average expected outcomes based on SRS difference and average actual outcomes for each seed over the past 12 years:From this angle, the No. 5 seed “outlier” doesn’t look as impressive. Seeds No. 1 through 6 all underperformed expectations by a smallish — but somewhat consistent — amount. The main difference with the No. 5 seed is that it didn’t have a big enough advantage to underperform this much without losing a lot more games.In other words, if there’s something that has systematically led tournament favorites to underperform their expectations by a few points or so across the board,4As a strictly mathy thing, having a somewhat constant deviation isn’t as weird as it may seem because the standard deviation for a team’s actual SRS is similarly stable. So in this case, it’s a bit like the stronger teams are all running one standard deviation below the expected mean. No. 5 seeds would be disproportionately hard-hit. Thus the 5-seed jinx may be more like the proverbial “canary in a coal mine,” indicating that something bigger is going on.We know the Big Dance is exciting, but could there really be something about the tournament that makes favorites underperform and gives underdogs better-than-normal chances?It’s tricky. For example, the selection committee may systematically overvalue particular types/classes of teams, but that doesn’t necessarily explain why teams would underperform relative to SRS. Some of it could be that SRS is poorly calibrated for the types of matchups we see in the tournament (e.g., between larger and smaller conferences that rarely play each other). It could be that favorites are more likely to regress to the mean.5This is always a good candidate, but, interestingly, there is no such effect in the women’s tournament.Or it could just be that this is March Madness, and anything can happen. If there’s one piece of folk wisdom that has emerged over the past decade or so of March Madness, it’s that No. 5 seeds are jinxed. SportsCenter did a whole story on the subject featuring Virginia Commonwealth University. In 2012, VCU was a No. 12 seed that pulled off a “shocking” upset against Wichita State. In 2013, VCU was itself a No. 5 but defied the trend, crushing No. 12 Akron by 46 points to become the only No. 5 seed to win its opening-round (round of 64) game that year. In 2014, VCU’s story came full circle. It again entered the tournament as a No. 5 seed but was upset by unheralded No. 12 seed Stephen F. Austin University. The tournament quirk that was once VCU’s magic was now its curse.Including those VCU games, No. 12 seeds over the past three years have pulled off upsets in eight of 12 round-of-64 matchups, including six of their last eight. It would be extremely easy to dismiss this as a freak occurrence. (I certainly did at first.) But it’s a real phenomenon. And after looking into it, I think it may be indicative of something larger. The 5-seed jinx may be a sign that March Madness — at least on the men’s side — is even madder than we think.But I’ll get there. First, let’s look at the phenomenon. If it seems like No. 12 seeds beat No. 5 seeds more than they should, it’s because they have. Going back to 1995, No. 5 seeds have been upset 33 times in 80 games. Their 59 percent win rate compares unfavorably to the 66 percent win rate of No. 6 seeds. Based on the trend, it would appear that No. 5 seeds should be winning more like 72 percent. Take a look at how far No. 5 seeds deviate in the chart below. The gray region is the standard error on the fit between seed and win percentage when not including the No. 5 seed:So they’re an outlier, but is it significant? Particularly, how unlikely is this to have happened by chance? Let us consult the oracle of binom.dist() — Excel’s handy function that tells you the probability of things happening a certain number of times, given the probability of them happening once. In a fun bit of symmetry, given an expected win rate of 72 percent, the odds of No. 5 seeds losing six of eight, eight of 12, or 33 of 80 are all about the same: Each is a little under 1 percent.10.8 percent, 0.6 percent and 0.7 percent, respectively.Note that it would be unremarkable for this to have happened by chance: One in a hundred-type things happen every day. But, as a committed Bayesian, I have to consult my priors and determine whether the phenomenon of No. 5 seeds’ underperforming is more likely to be a result of chance or other plausible factors.First, let’s look at how strong each seed’s teams have been since 1995. As you go from the 1 vs. 16 matchups down to the 8 vs. 9 ones, the better-seeded teams get worse and the worse-seeded teams get better, making the contests much closer. To see how much so, we can plot each team’s SRS (Simple Rating System, a metric that measures margin of victory adjusted for strength of schedule) prior to the game.2I backed these out myself, so there may be very small differences from what was actually recorded at the time. They’re as prior to each team’s round-of-64 match for each year (since 1995).
The NanoSteel Company, a leader in nano-structured steel materials design, has had its Super Hard Steel® (SHS) weld alloy selected by Trimay Wear Plate Ltd to provide wear protection within the steel piping of a concrete slick line at an underground mine in Northern Canada. NanoSteel said that its “superior wear performance has been proven to provide a x30 wear rate improvement over the previous solution.” Combined with Trimay’s unique casing design, this project represents the second line with an identical configuration developed for the customer and will be installed during the first quarter of 2014.The slick line is a 600 m vertical borehole system of 9 5/8 in diameter casing used for delivering concrete to backfill mined out sections and reinforce rock walls so the next ore body segment can be mined safely. It consists of NanoSteel clad API L80 grade steel casing and Trimay’s proprietary threaded joint system. In its initial installation, thickness loss for the NanoSteel cladding was measured at 0.9 mm, after delivering 120,000 m3 (288,000 t) of concrete over 30 months of service. With this demonstrated wear rate of 320,000 t delivered per mm of thickness loss, the coated pipe has provided a x30 improvement over the previous solution – an uncoated API L80 bare casing with a wear rate of 10,500 t/mm. Service life for the system is projected to achieve full “life of mine” duration, exceeding 19 years.“The high hardness and toughness properties provided by our weld overlay result in the improved wear performance for this application,” said Tom Santos, Vice President and General Manager of Coatings. “Because of this, a slick line clad with our material eliminates several replacement cycles for a life of mine solution.” Trimay’s Doug Fraser, General Manager, added, “For this vertical slick line application, Trimay’s casing design provides significant time and cost savings at installation. Compared to casing lines with welded flange connections, our threaded joint system connected by a zero-differential coupling can be fitted in the field more than x70 faster and allow a smaller diameter borehole to be drilled at a lower cost.”
Egyptian handball Federation announced negotiations with Spanish coach Xavi Sabate on the official Facebook page.“It was fruitful 24 hours visit”, wrote Egyptians on their page.Egyptians looking for a new coach after Africa Championship, where they ended with silver medal.Xavi Sabate worked with Telekom Veszprem and Hungarian national team. He led Hungarian champions at VELUX EHF Champions League Final 2016, while Hungary played at quarter-final of the WOrld Championship 2017 in France after beating Denmark at TOP 16. egyptXavi Sabate ← Previous Story THE END OF SERIES: Pick Szeged conquer “Veszprem Arena” Next Story → Women’s EHF CL 17/18 1/4 finals: “Classic” between Gyor and Buducnost!
WASHINGTON — On their first day in the majority, House Democrats on Thursday night passed a plan to re-open the government without funding President Donald Trump’s promised border wall.The largely party-line votes came after Trump made a surprise appearance at the White House briefing room pledging to keep up the fight for his signature campaign promise.House Speaker Nancy Pelosi said Trump and Senate Republicans should “take yes for an answer” and approve the border bill, which was virtually identical to a plan the Senate adopted on a voice vote last month.“We’re not doing a wall. Does anyone have any doubt that we’re not doing a wall?” Pelosi told reporters at a news conference Thursday night.Pelosi, who was elected speaker earlier Thursday, also took a shot a Trump, calling his proposal “a wall between reality and his constituents.”Trump strode into the White House briefing room Thursday — the 13th day of the partial government shutdown —and declared that “without a wall you cannot have border security.” He then left without taking questions from reporters.The appearance came hours after the new Congress convened, with Democrats taking majority control of the House and returning Pelosi to the speakership after eight years of GOP control. The Democratic legislation to re-open the government without funding the wall is going nowhere in the Senate, where Republicans want Trump’s endorsement before voting on a funding package.
After dishing out over £100m in the summer for “quality” players, Fulham are bottom of the Premier League table, but Tom Cairney believes they deserve better.Despite making 12 news signing and spending over £100m in the summer transfer window, Fulham have conceded the most goals and are stuck to the bottom of the league table this season.Manager Slavisa Jokanovic was sacked as a result, and former Leicester City boss Claudio Ranieri was appointed to help the club survive relegation.“We spent around £100m – a record amount for a newly-promoted team,” Cairney told the Daily Mail. “The owners have backed us, and with the quality, we have in the squad we shouldn’t be where we are.Official: Tottenham sign Fulham youngster Ryan Sessegnon Andrew Smyth – August 8, 2019 Tottenham have sealed another transfer deadline day deal to sign the highly-rated Ryan Sessegnon from Fulham.“When you bring a lot of new players in, that is the hardest thing; getting everyone playing together. The gaffer knows that.“He took all the players and staff for an Italian on Wednesday – and now it is about building something.“We simply have to keep clean sheets because we have conceded a lot of goals. We need to improve defensively.”
The door to Fansler’s office in the Capitol was locked Monday morning, two days after House Speaker Bryce Edgmon called for Fansler to resign. Facebook0TwitterEmailPrintFriendly分享JUNEAU, Alaska (AP) A spokesman for the House Majority Coalition says staff members for Alaska state Rep. Zach Fansler have been reassigned. Mike Mason says Fansler’s staff has been reassigned to the House Rules chair’s office. The resignation call came after a Juneau Empire report in which a woman alleged Fansler hit her during a night of drinking. Fansler’s attorney has said there was no crime.
ReutersThe ‘battle’ between and India and China for a key stake in Dhaka Stock Exchange (DSE) has entered the final lap with the Bangladesh Security Exchange Commission (BSEC) set to pick a bidder on Monday. Consortiums led by Indian and Chinese bourses have been in the fray for a 25 percent stake in the third largest capital market in Asia. A win in Bangladesh will be another feather on the cap of China, which picked up a 40 percent stake in the Pakistan Stock Exchange last year. And for India, a loss of turf in Bangladesh will be another wound to nurse in the backdrop of rising Chinese influence in its backyard.The drama surrounding the DSE stake sale, however, suggests that the consortium led by India’s National Stock Exchange (NSE) might pull off a victory despite having submitted a much smaller bid price than the Chinese consortium.China’s Shanghai and Shenzen stock exchanges offered 22 takas ($0.26) each for the 2.8 billion shares on offer in DSE, while the NSE, Frontier Bangladesh and US bourse Nasdaq offered only 15 takas per share. The Chinese offer also came bundled with a proposal for technical support to DSE worth around $37 million. While NSE also offered technical support, the value of the proposal was unspecified.What appeared to be a normal bid process soon became a complicated power play after news emerged that DSE ‘selected’ the Chinese bid. “The consortium of Shanghai and Shenzhen stock exchanges has been chosen from the two consortiums that submitted proposals, considering capabilities, competitive bids and everything,” a DSE director told BD News on February 6.The Indian authorities apparently swung into action as the rival regional power sealed a toe hold in its sphere of influence. India couldn’t have done anything to prevent China from picking up a stake in Pakistan’s only bourse, but in Bangladesh, Indian diplomatic pressure has apparently tilted the scale in its favour.NSE managing director and CEO, Vikram Limaye, travelled to Bangladesh last week, where he held discussions with the officials of DSE and the Bangladesh market regulator. After the meeting the Daily Star reported that the BSEC asked the DSE board to scrutinise the rival proposals again. BSEC Executive Director Saifur Rahman, who was quoted in the story, did not confirm if the Chinese bid had been rejected, though earlier media reports had suggested so.Yuan-denominated financial productsThe Indian side is reported to have convinced the Bangladeshi counterparts that though the Indian bourse’s offer price was almost 50 percent lower than the Chinese bid, they had better expertise in running a bourse. India appears to have outmanoeuvred the Chinese in the first round, having forced the Bangladeshi regulator to scupper a straight-laced plan by the DSE to accept the Chinese offer.It’s interesting to watch how the dice turns — whether India’s close ties with Prime Minister Sheikh Hasina will tilt the balance in its favour or if the Chinese will have the last laugh. Given the fact that the Bangladesh government will have a final say in this, it will also be a stray in the wind as far as China’s geopolitical push in India’s backyard is concerned.For China, a successful bid will mean an easy extension of its footprint in the region. More importantly, in the long-term, it will even help China in its efforts to make Yuan a major international currency. Again, if China is able to list Yuan-denominated financial products on the Dhaka bourse in future, it will help the expansion of Chinese companies in Bangladesh.
X Share 00:00 /00:45 – / 7 It’s costing $962 million dollars to replace the Ship Channel Bridge and it’s the biggest infrastructure project Harris County has ever undertaken.The Harris County Toll Road Authority says it’s replacing the bridge so it can handle growing traffic. The bridge currently carries about 55,000 vehicles a day. That’s expected to grow to about 160,000 vehicles a day by 2035.The replacement project includes four lanes in each direction and it’ll look a lot like the Fred Hartman Bridge near Baytown.William Torres is Deputy Program Manager at HNTB, the firm that’s overseeing the project.“The bridge is really designed for the motorist,” said Torres. “Driving along the roadway you will see a beautiful cable-stayed bridge with towers over 500 feet tall, providing aesthetic lighting at night for a completely immersive experience.”Torres said the cable-stayed design allows for deep foundations to accommodate soil conditions. And since there won’t be pylons in the middle of the water the Ship Channel will be easier to dredge.“Doing this method allows for constructing the bridge essentially in the same footprint and there was no need for additional right-of-way,” added Torres.HCTRA’s Roxana Sibrian said the new bridge will be a huge improvement in terms of safety. The current bridge only has two lanes each way with no place to pull over.“Currently if a driver for one reason or another breaks down the roadway shuts down,” explains Sibrian. “And that’s not favorable for drive times.”The entire project will take about six-and-a-half years with the southbound span set for completion in 2021. All traffic will then be switched to the southbound bridge while they tear down the current bridge and build the northbound span. HCTRA says all work should be finished by 2024.Sibrian said they plan to keep traffic moving throughout the entire effort.“There will be passage through the area at all times and that was something that was thought of in advance,” said Sibrian. “Drivers will just need to know we will be communicating actively if there is any disruption but we anticipate that passage will be available for our drivers.”The Ship Channel Bridge was converted to all-electronic tolling in 2016 and Sibrian said tolls will remain in effect while construction is underway. To embed this piece of audio in your site, please use this code: Listen
They opted for biorobots made of sperm cells and turned to bull sperm cells, Schmidt said, according to New Scientist, that reasons why sperm cells were an attractive choice were that they were harmless to the body, they could swim through viscous liquids, and they did not need any external power source. The researchers produced microtubes and worked with thawed-out bull sperm cells, remaining viable for several hours. According to New Scientist, the microtubes are made from iron and titanium nanoparticles. Scientists have shown how controlled sperm cells inside tubes can be driven to target destinations using magnetic control. The significance of their investigation lies partly in what may be in store for in vitro fertilization. “Eventually,” said a report in New Scientist, “these biobots could be used to shepherd individual sperm to eggs or to deliver targeted doses of drugs.” The researchers, from the Institute for Integrative Nanosciences (IIN) in Dresden, Germany, demonstrated how remote-controlled “sperm-bots” can be used to fertilize eggs. A paper on their work was published last month in Advanced Materials and the topic continues to draw interest in this month’s technology and science news sites. The December paper, “Development of a Sperm-Flagella Driven Micro-Bio-Robot,” is by Veronika Magdanz, Samuel Sanchez, and Oliver G. Schmidt. They developed “a new biohybrid micro-robot” by capturing bovine sperm cells inside tubes that used the motile cells as the driving force. An external magnetic field controlled the robots. More information: Press release in GermanPaper: Development of a Sperm-Flagella Driven Micro-Bio-Robot, Advanced Materials, DOI: 10.1002/adma.201302544AbstractA new biohybrid micro-robot is developed by capturing bovine sperm cells inside magnetic microtubes that use the motile cells as driving force. These micro-bio-robots can be remotely controlled by an external magnetic field. The performance of micro-robots is described in dependence on tube radius, cell penetration, and temperature. The combination of a biological power source and a microdevice is a compelling approach to the development of new microrobotic devices with fascinating future applications. Journal information: Advanced Materials Researchers discover sperm move along a ‘twisting ribbon’ Credit: Leibniz-Institut für Festkörper- und Werkstoffforschung Dresden Schmidt, the Institute’s director, and his IIN colleagues combined the cells with magnetic metal tubes. Basically, the investigation involved live flagella from bull sperm to maneuver nanotubes in a desired direction using magnets. Changes in temperature were able to control their speeds.According to a report on their work in Gizmag, the team intends to try assisted fertilization with animals before starting experiments with human sperm. One additional possibility is that their research might impact future investigations in targeted drug delivery, where drugs may be ferried along within the body. Another interesting feature about this research is how it involves use of “biobots” as opposed to artificial engines. As Gizmag noted, a concern in research is that a nanobot intended to move through bodily fluids should not be toxic to the human body and should not cause harm to cells, affecting their functioning. The IIN scientists discussed safe “nano-engine” alternatives, or suitable “biorobots.” Explore further PausePlay% buffered00:0000:00UnmuteMuteDisable captionsEnable captionsSettingsCaptionsDisabledQuality0SpeedNormalCaptionsGo back to previous menuQualityGo back to previous menuSpeedGo back to previous menu0.5×0.75×Normal1.25×1.5×1.75×2×Exit fullscreenEnter fullscreen Play Credit: Leibniz-Institut für Festkörper- und Werkstoffforschung Dresden Citation: Sperm-bots are made to move in desired direction (w/ Video) (2014, January 17) retrieved 18 August 2019 from https://phys.org/news/2014-01-sperm-bots-desired-video.html © 2014 Phys.org This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
© 2015 Phys.org Play In vivo label-free SRS imaging cell division dynamics in cancer. Synchronized HeLa cells were injected into a xenograft mouse model with a skinfold chamber. Imaging was taken 26 h after the injection. Cells in mitotic phase that landed in the subskin tissue microenvironment (protein contrast in blue) were targeted and imaged. Chromosomal dynamics were captured based on DNA contrast (magenta). The video was composed of 12 frames acquired with a 3-min interval. Credit: PNAS, Fa-Ke Lu, doi: 10.1073/pnas.1515121112 To prove that their technique would work, they analyzed samples of synthetic DNA, BSA (protein) and oleic acid (lipid), individually and collectively in a cellular pellet. They measured the three Raman vibrational shifts and calculated the distribution of DNA, protein and lipid using linear decomposition. This study confirmed not only that their technique worked, but that it is also highly accurate.The next step was to test their technique in biological samples. Lu, et al. used their SRS technique to look at cell division in HeLa cells. They first looked at cells in the first stage of mitosis, the prophase, and were able to reconstruct a 3D distribution of DNA, lipids, and protein, showing a high concentration of DNA in the nucleus, lipids predominantly in the cytoplasm, and proteins scattered throughout the entire cell. They then imaged cells in at the interphase stage of mitosis and were able to discern the chromatin structures in the nuclei. Time-lapse SRS allowed Lu, et al. to observe the transition from metaphase to anaphase. Explore further PausePlay% buffered00:0000:00UnmuteMuteDisable captionsEnable captionsSettingsCaptionsDisabledQuality0SpeedNormalCaptionsGo back to previous menuQualityGo back to previous menuSpeedGo back to previous menu0.5×0.75×Normal1.25×1.5×1.75×2×Exit fullscreenEnter fullscreen To really understand what is happening during cellular processes, including cellular malfunctioning as in cancer, there is a need to peer inside the cell without disrupting any of the cellular processes. Typically if scientists want to look at large spools of DNA, known as chromosomes, they would need to fluorescently label the DNA. This approach is invasive and may alter the native environment of the cell.Furthermore, in medicine, histological diagnoses are typically done by examining stained tissue biopsies. In this study, Fa-Ke Lu, Srinjan Basu, Vivien Igras, Mai P. Hoang, Minbiao Ji, Dan Fu, Gary R. Holtom, Victor A. Neel, Christian W. Freudiger, David E. Fisher, and X. Sunney Xie present a label-free technique that forgoes staining and could potentially offer a non-invasive way to diagnose skin cancer.Stimulated Raman scattering (SRS) microscopy is a type of imaging technique that looks at the vibrational frequencies of chemical bonds. Different types of bonds will have different frequencies based on the surrounding molecular environment. For example, a C-H bond on a DNA molecule (2,956 cm-1) is going to have a slightly different vibrational frequency compared to a C-H bond on proteins (2,931 cm-1) or lipids (2,854 cm-1). Unlike traditional Raman spectroscopy, SRS is able to obtain data on a sample rapidly, allowing for real-time, in vivo studies. By looking at these C-H stretching vibration regions and conducting a linear decomposition of the images, Lu, et al. were able to map the content and distribution of DNA, proteins, and lipids within the cell, allowing them to observe the cell division process in a label-free manner. Journal information: Proceedings of the National Academy of Sciences Citation: Label-free technique that images DNA in vivo (2015, September 9) retrieved 18 August 2019 from https://phys.org/news/2015-09-label-free-technique-images-dna-vivo.html Imaging glucose uptake activity inside single cells (Phys.org)—A group of researchers from Harvard University report being able to observe DNA dynamics during cell division in vivo using time-lapse stimulated Raman scattering microscopy and without using fluorescent labels. Their work appears in the Proceedings of the National Academy of Sciences. More information: “Label-free DNA imaging in vivo with stimulated Raman scattering microscopy” PNAS, Fa-Ke Lu, DOI: 10.1073/pnas.1515121112AbstractLabel-free DNA imaging is highly desirable in biology and medicine to perform live imaging without affecting cell function and to obtain instant histological tissue examination during surgical procedures. Here we show a label-free DNA imaging method with stimulated Raman scattering (SRS) microscopy for visualization of the cell nuclei in live animals and intact fresh human tissues with subcellular resolution. Relying on the distinct Raman spectral features of the carbon-hydrogen bonds in DNA, the distribution of DNA is retrieved from the strong background of proteins and lipids by linear decomposition of SRS images at three optimally selected Raman shifts. Based on changes on DNA condensation in the nucleus, we were able to capture chromosome dynamics during cell division both in vitro and in vivo. We tracked mouse skin cell proliferation, induced by drug treatment, through in vivo counting of the mitotic rate. Furthermore, we demonstrated a label-free histology method for human skin cancer diagnosis that provides comparable results to other conventional tissue staining methods such as H&E. Our approach exhibits higher sensitivity than SRS imaging of DNA in the fingerprint spectral region. Compared with spontaneous Raman imaging of DNA, our approach is three orders of magnitude faster, allowing both chromatin dynamic studies and label-free optical histology in real time. In vivo studies were done on the skin of mice treated with TPA, a chemical that promotes cell division. Lu, et al. were able to discern each stage of the cell cycle as described before. Additionally, they were able to look at chromosomal migration in cancer cells from immune-deficient mice treated with human cancer cells. These results then lead Lu, et al. to use time-lapse SRS to study cell cycle kinetics. By understanding the rate at which cells divide, researchers can discern important factors, such as the aggressiveness of a cancer. They found that in TPA-treated mice, cell mitotic activity peaked at 18 hours and by 24 hours had decreased. This was the first time that a mitotic rate was reported in vivo in a quantitative manner.The last step was to test their label-free SRS technique with human cancer cells to see if it is a viable technique for histologic diagnosis. To ensure the accuracy of their technique, they first imaged a tissue sample using traditional staining and compared it to their SRS technique. They then imaged fresh human skin cancer tissue from three surgical cases of squamous cell carcinoma, the second most common form of skin cancer. They found an increased number of mitotic features, which translates into increased cell division and proliferation, hallmarks of cancer cells. Their results demonstrate that their label-free SRS imaging method is comparable to traditional staining methods for histological diagnosis. Additionally, because SRS allows for the observation of nucleic acids, specifically, researchers can do quantitative studies of mitotic kinetics within a tumor cell.According to co-author Professor Xie, “SRS imaging could be particularly relevant for in vivo counting of the mitotic rate used in human skin cancer diagnosis. We expect that SRS may not only speed up surgical procedures by on-site label-free imaging of tumor tissue with margins, but it could also have the potential for in vivo noninvasive detection and progress evaluation of skin lesions in real time.”This technique holds much promise for being used both as a non-invasive method for skin cancer diagnosis, and as a quick evaluation of the aggressiveness of cancer cells after excision.Co-author Dr. David Fisher adds that “this remarkable methodology provides high resolution images of cells and their nuclei within their natural biological context, providing a novel means of tracking their behavior over time. SRS is a particularly valuable tool for the evaluation of cancer cells.” In vitro label-free SRS imaging of cell division dynamics of a cultured HeLa cell. Credit: PNAS, Fa-Ke Lu, doi: 10.1073/pnas.1515121112 This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
Kolkata: The year is going to end on a sweet note for the people of Kolkata as a three-day ‘rosogolla’ festival is being organized in the city to pay tribute to its inventor Nobin Chandra Das. Bengal had last year received a Geographical Indication (GI) tag for the round-shaped syrupy sweet. The three-day gala, beginning December 28, will celebrate 150 years of ‘rosogolla’ invention, said West Bengal minister Sashi Panja. “The first-ever ‘Baghbazar-O-Rosogolla Utsab’, supported by the state government, is aimed at paying tribute to Das and his invention of the syrupy cheeseball, which went on to conquer taste buds across the world,” Panja, who is also the chief convener of the fest, told reporters here recently. Also Read – Rain batters Kolkata, cripples normal life The sweetmeat festival will also highlight the history, heritage and culture of Baghbazar – the hub of the Bengal renaissance, she said. Singer Hariharan is set to grace the occasion and enthrall visitors with his performance. The fest committee, with painter Suvaprasanna as chief adviser and the rosogolla inventor’s heir Dhiman Das as member, has also arranged for cooking competitions and quiz contests. Sweetmeat traders from across the state will get an opportunity to dish out their signature items during the three-day fiesta, Panja, the state minister for women and child development and social welfare, said. Also Read – Speeding Jaguar crashes into Mercedes car in Kolkata, 2 pedestrians killed “I fell very proud that Rosogolla has been invented in this city, in Baghbazar. We will also observe 100 years of Bagbazar Sarbojanin Durgotsav (annual Durga puja) at the fest,” she added. Nobin Chandra Das had opened a sweet shop at Jorasanko in north Kolkata in 1864, but he tasted success after moving his business to Baghbazar in 1866. It was sometime in 1868, when he created ‘rosogolla’ out of fragmented clumps of cottage cheese and sugar syrup.
11 Comments Share Smith warned him that he needs to bulk up and watch out for defenders as he throws.“He looks like he needs to be in a weight room just as much as me, and then on top of it all, you’re going into the NFL … they have a license to assault you!” Smith said. “So even if you’re flinging passes, you could still get knocked upside the head after you release the ball.”That’s right, even though contact after the throw is illegal, it still happens in the NFL. Rosen needs to be careful of this.Smith acknowledged that he had no worries about Rosen’s ability to play football, simply his durability. He could get concussed again against the grown men in the NFL.“You’re chirping already?” Smith exclaimed loudly. “It is stupid and he needs to be quiet.” – / 97 The 5: Takeaways from the Coyotes’ introduction of Alex Meruelo Grace expects Greinke trade to have emotional impact Top Stories Derrick Hall satisfied with D-backs’ buying and selling Former Cardinals kicker Phil Dawson retires In less than 24 hours of being a professional, Josh Rosen has already made a host of notable quotes.Perhaps his hottest take: “There were nine mistakes made ahead of me. I will make sure over the next decade or so they know they made a mistake.”Will he regret telling nine teams they made a mistake drafting him? Let’s go to ESPN’s Stephen A. Smith for comment.“Well yes, I do (think so), because I think he’s an idiot,” Smith said. “And I’m going to say it on national television, to this guy who’s supposed to be so intelligent, his IQ is supposed to be off the charts – enough of this already.” Stephen A. Smith, best known for saying his opinion loudly on ESPN’s First Take with Skip Bayless (and now Max Kellerman), thinks that Rosen is dumb for saying he should have been the first quarterback taken.Smith later clarified that he’s “not calling him an idiot literally, of course he’s a smart young man.”“I’m calling him idiotic, rather, because you are walking into the National Football League, going up against men,” he said.So, to backtrack: Smith doesn’t think Rosen is an idiot. You can calm down, Arizona.Smith simply thinks Rosen is idiotic.Related LinksPissed, motivated and determined: The best quotes from Josh RosenCardinals view Josh Rosen’s outspoken personality as a plusDilfer: Cardinals won draft with Rosen pick, QB has Rodgers-type talentThe ESPN analyst is concerned with Rosen’s durability. In 2016, Rosen injured his shoulder and missed half the season. In 2017, he suffered two concussions and missed the Cactus Bowl. UCLA cited injury, though he wanted to play.Smith addressed Rosen directly:“Let me ask you a question, Josh Rosen: When somebody knocks you upside your head or caves your chest in to the point where you’re gasping for air because a grown man put you down, what does that have to do with anything? What are you going to do then?”He means that there’s a big difference between facing college and professional athletes. Guys in the NFL are bigger, faster and stronger than any other level of competition. Rosen will have to adjust, or he may not last long in the league, especially with his history of injuries.
Go back to the e-newsletterEmirates and Thales have signed a new agreement to equip the Boeing 777X fleet with next-generation broadband inflight connectivity using the Inmarsat GX global network. The partnership will give Emirates customers best-in-class connectivity aboard the Boeing 777X aircraft, due for delivery starting in 2020.Emirates and Thales already have an existing multi-million-dollar deal to fit the Boeing 777X fleet with a Thales AVANT inflight entertainment system. The new agreement is part of the Emirates and Thales’ plans to develop and enhance the state-of-the-art inflight entertainment and connectivity (IFEC) on the 777X fleet.Over the years, Emirates has invested more than US$200 million to equip its aircraft with connectivity. Demand for Wi-Fi onboard has been steadily increasing and today over 800,000 passengers per month connect while inflight. Emirates offers all its customers 20MB of complimentary Wi-Fi data on board while Emirates Skywards members in First Class and Business Class enjoy unlimited complimentary Wi-Fi and discounted plans in Economy Class.Emirates, Thales and Inmarsat have invested heavily in the new-generation Wi-Fi solution and will work together to meet increasing demand for Wi-Fi on board. Broadband connectivity speeds coupled with Thales’ AVANT innovative and highly customisable IFE system will provide a further boost to Emirates’ award-winning inflight entertainment system, ice.Emirates is the largest operator of the Boeing 777 aircraft, one of the most popular and advanced wide-bodied aircraft in commercial operation today. The airline has 165 Boeing 777s in its fleet, and a further 164 on firm order, including 150 of the next-generation Boeing 777X aircraft.Go back to the e-newsletter